OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 4gwk [A]

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Title

CRYSTAL STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE COMPLEXED WITH 3-PHOSPHOGLYCERIC ACID

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
4gwk			23153533	X-RAY DIFFRACTION/1.53	3PG:3-PHOSPHOGLYCERIC ACID MES:2-(N-MORPHOLINO)-ETHANESULFONIC ACID

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A]	[A]	[A]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
222255	A:178-470	All alpha proteins	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain	automated matches	Human (Homo sapiens) [TaxId: 9606]
222254	A:2-177	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Human (Homo sapiens) [TaxId: 9606]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
4gwkA01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
4gwkA02	1.10.1040.10		:Orthogonal Bundle	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	:N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2