PDB ID : 4ii2 [ABC]
Color
ARa IRb
|
|
a AR:All Residues
b IR:Interface Residues
b IR:Interface Residues
Slab plane
Title
CRYSTAL STRUCTURE OF UBIQUITIN ACTIVATING ENZYME 1 (UBA1) IN COMPLEX WITH THE UB E2 UBC4, UBIQUITIN, AND ATP/MG
Structure Summary
| PDB ID | Mutant | OPM | Pub Med | Method/Resolution | HETNAM |
|---|---|---|---|---|---|
| 4ii2 | 23416107 | X-RAY DIFFRACTION/2.2 | ATP:ADENOSINE-5___sq___-TRIPHOSPHATE EDO:1,2-ETHANEDIOL MG:MAGNESIUM ION PG0:2-(2-METHOXYETHOXY)ETHANOL SO4:SULFATE ION |
| Chain Formula | ||
|---|---|---|
| Amino Acid sequence | SCOPe Family Level | CATH Homology Level |
| [ABC] | [ABC] | [ABC] |
Structual Classification
SCOPe
| SCOPe ID | Chain | Class | Fold | Superfamily | Family | Protein Domain | Species |
|---|---|---|---|---|---|---|---|
| 298394 | B:-3-0 | Artifacts | Tags | Tags | Tags | N-terminal Tags | Synthetic |
| 196616 | B:1-76 | Alpha and beta proteins (a+b) | beta-Grasp (ubiquitin-like) | Ubiquitin-like | Ubiquitin-related | automated matches | Schizosaccharomyces pombe [TaxId: 284812] |
| 196619 | C:1-147 | Alpha and beta proteins (a+b) | UBC-like | UBC-like | UBC-related | automated matches | Schizosaccharomyces pombe [TaxId: 284812] |
| 298395 | C:148-149 | Artifacts | Tags | Tags | Tags | C-terminal Tags | Synthetic |
CATH
| CATH ID | Node | Class | Architecture | Topology | Homology |
|---|---|---|---|---|---|
| 4ii2A01 | 3.50.50.80 | :3-Layer(bba) Sandwich | :FAD/NAD(P)-binding domain | :Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 | |
| 4ii2A02 | 3.40.50.12550 | :3-Layer(aba) Sandwich | :Rossmann fold | :Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2 | |
| 4ii2A03 | 2.40.30.180 | :Beta Barrel | :Elongation Factor Tu (Ef-tu); domain 3 | :Ubiquitin-activating enzyme E1, FCCH domain | |
| 4ii2A04 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain | |
| 4ii2A05 | 1.10.10.2660 | :Orthogonal Bundle | :Arc Repressor Mutant, subunit A | :Ubiquitin-activating enzyme E1, SCCH domain | |
| 4ii2A06 | 3.10.290.60 | :Roll | :Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A | :Ubiquitin-activating enzyme E1, UFD domain | |
| 4ii2B00 | 3.10.20.90 | :Roll | :Ubiquitin-like (UB roll) | :Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | |
| 4ii2C00 | 3.10.110.10 | :Roll | :Ubiquitin Conjugating Enzyme | :Ubiquitin Conjugating Enzyme |
