PDB ID : 4lrt [A2B2]
Color
ARa IRb
|
|
a AR:All Residues
b IR:Interface Residues
b IR:Interface Residues
Slab plane
Title
CRYSTAL AND SOLUTION STRUCTURES OF THE BIFUNCTIONAL ENZYME (ALDOLASE/ALDEHYDE DEHYDROGENASE) FROM THERMOMONOSPORA CURVATA, REVEAL A COFACTOR-BINDING DOMAIN MOTION DURING NAD+ AND COA ACCOMMODATION WHITHIN THE SHARED COFACTOR-BINDING SITE
Structure Summary
| PDB ID | Mutant | OPM | Pub Med | Method/Resolution | HETNAM |
|---|---|---|---|---|---|
| 4lrt | Not in PubMed | X-RAY DIFFRACTION/1.5 | COA:COENZYME A GOL:GLYCEROL MG:MAGNESIUM ION NA:SODIUM ION PYR:PYRUVIC ACID SO4:SULFATE ION |
| Chain Formula | ||
|---|---|---|
| Amino Acid sequence | SCOPe Family Level | CATH Homology Level |
| [A2B2] | [A2B2] | [A2B2] |
Structual Classification
SCOPe
| SCOPe ID | Chain | Class | Fold | Superfamily | Family | Protein Domain | Species |
|---|---|---|---|---|---|---|---|
| 235501 | A:10-294 | Alpha and beta proteins (a/b) | TIM beta/alpha-barrel | Aldolase | automated matches | automated matches | Thermomonospora curvata [TaxId: 471852] |
| 235502 | A:295-343 | All alpha proteins | RuvA C-terminal domain-like | post-HMGL domain-like | automated matches | automated matches | Thermomonospora curvata [TaxId: 471852] |
| 235503 | C:11-294 | Alpha and beta proteins (a/b) | TIM beta/alpha-barrel | Aldolase | automated matches | automated matches | Thermomonospora curvata [TaxId: 471852] |
| 235504 | C:295-345 | All alpha proteins | RuvA C-terminal domain-like | post-HMGL domain-like | automated matches | automated matches | Thermomonospora curvata [TaxId: 471852] |
CATH
| CATH ID | Node | Class | Architecture | Topology | Homology |
|---|---|---|---|---|---|
| 4lrtA01 | 3.20.20.70 | :Alpha-Beta Barrel | :TIM Barrel | :Aldolase class I | |
| 4lrtA02 | 1.10.8.60 | :Orthogonal Bundle | :Helicase, Ruva Protein; domain 3 | : | |
| 4lrtB01 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain | |
| 4lrtB02 | 3.30.360.10 | :2-Layer Sandwich | :Dihydrodipicolinate Reductase; domain 2 | :Dihydrodipicolinate Reductase; domain 2 | |
| 4lrtC01 | 3.20.20.70 | :Alpha-Beta Barrel | :TIM Barrel | :Aldolase class I | |
| 4lrtC02 | 1.10.8.60 | :Orthogonal Bundle | :Helicase, Ruva Protein; domain 3 | : | |
| 4lrtD01 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain | |
| 4lrtD02 | 3.30.360.10 | :2-Layer Sandwich | :Dihydrodipicolinate Reductase; domain 2 | :Dihydrodipicolinate Reductase; domain 2 |
