PDB ID : 4nd4 [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CA
DB
Title
CRYSTAL STRUCTURE OF THE LACTATE DEHYDROGENASE FROM CRYPTOSPORIDIUM PARVUM COMPLEXED WITH SUBSTRATE (PYRUVIC ACID) AND COFACTOR (B- NICOTINAMIDE ADENINE DINUCLEOTIDE)

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
4nd4
25542170 X-RAY DIFFRACTION/2.2 GOL:GLYCEROL
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
PYR:PYRUVIC ACID
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
261820 A:165-333Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainLactate dehydrogenaseCryptosporidium parvum [TaxId: 5807]
261818 A:17-164Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsLDH N-terminal domain-likeLactate dehydrogenaseCryptosporidium parvum [TaxId: 5807]
261822 B:165-333Alpha and beta proteins (a+b)LDH C-terminal domain-likeLDH C-terminal domain-likeLactate & malate dehydrogenases, C-terminal domainLactate dehydrogenaseCryptosporidium parvum [TaxId: 5807]
261819 B:17-164Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsLDH N-terminal domain-likeLactate dehydrogenaseCryptosporidium parvum [TaxId: 5807]

CATH
CATH ID Node Class Architecture Topology Homology
4nd4A013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4nd4A023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4nd4B013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4nd4B023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal