PDB ID : 4piv [A]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

Direction Proportion
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From back %
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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
Title
HUMAN FATTY ACID SYNTHASE PSI/KR TRI-DOMAIN WITH NADPH AND GSK2194069

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
4piv
25086508 X-RAY DIFFRACTION/2.3 2W4:4-[4-(1-BENZOFURAN-5-YL)PHENYL]-5-{[(3S)-1-(CYCLOPROPYLCARBONYL)PYRROLIDIN-3-YL]METHYL}-2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE
CAC:CACODYLATE ION
NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE
SO4:SULFATE ION
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A] [A] [A]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
414143 A:1109-1406Alpha and beta proteins (a/b)S-adenosyl-L-methionine-dependent methyltransferasesS-adenosyl-L-methionine-dependent methyltransferasesautomated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]
414144 A:1407-1522Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]
414145 A:1877-2113Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]
414146 B:1110-1406Alpha and beta proteins (a/b)S-adenosyl-L-methionine-dependent methyltransferasesS-adenosyl-L-methionine-dependent methyltransferasesautomated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]
414147 B:1407-1522Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]
414148 B:1877-2113Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesHuman (Homo sapiens) [TaxId: 9606]

CATH
CATH ID Node Class Architecture Topology Homology
4pivA023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4pivB023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain