PDB ID : 4qt0 [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
CRYSTAL STRUCTURE OF HUMAN MUSCLE L-LACTATE DEHYDROGENASE IN COMPLEX WITH INHIBITOR 1, 3-{[3-CARBAMOYL-7-(2,4-DIMETHOXYPYRIMIDIN-5-YL) QUINOLIN-4-YL]AMINO}BENZOIC ACID

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
4qt0
25664730 X-RAY DIFFRACTION/3.2 38Q:3-{[3-CARBAMOYL-7-(2,4-DIMETHOXYPYRIMIDIN-5-YL)QUINOLIN-4-YL]AMINO}BENZOIC ACID
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
x9690_Not ClassifiedNot Classified 96Not Classified 96Not Classified 96Not Classified 96Not Classified 9690

CATH
CATH ID Node Class Architecture Topology Homology
4qt0A013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qt0A023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4qt0B013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qt0B023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4qt0C013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qt0C023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4qt0D013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qt0D023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4qt0E013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qt0E023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4qt0F013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qt0F023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4qt0G013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qt0G023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
4qt0H013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qt0H023.90.110.10:Alpha-Beta Complex:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal