PDB ID : 4qxm [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

Style





Secondary Structure


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Slab plane

Direction Proportion
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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BC
CE
DG
Title
CRYSTAL STRUCTURE OF THE INHA:GSK_SB713 COMPLEX

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
4qxm
26934341 X-RAY DIFFRACTION/2.2 713:N-(2-CHLORO-4-FLUOROBENZYL)-4-[(3,5-DIMETHYL-1H-PYRAZOL-1-YL)METHYL]BENZAMIDE
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
275213 A:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
275214 C:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
275216 E:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
275217 G:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

CATH
CATH ID Node Class Architecture Topology Homology
4qxmA003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qxmC003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qxmE003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4qxmG003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain