OLIGAMI : Oligomer Architecture and Molecular Interface

Title

THE CRYSTAL STRUCTURE OF THE TERMINAL R DOMAIN FROM THE MYXALAMID PKS- NRPS BIOSYNTHETIC PATHWAY

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
4u7w			26235055	X-RAY DIFFRACTION/1.9	ACT:ACETATE ION MSE:SELENOMETHIONINE NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A2]	[A2]	[A2]

Interfaces

Interface ID	Chain	Inaterface Class	Interface Type	Contact Type
4u7w_AB	A B	HN HN	i4_CR(H9,N8)_HN(L1,S2) i4_CR(H9,N8)_HN(L1,S2)	c5_RP(HH26,NN4,HN7,NH7)_HH(P1,A1,S1)_HN(L2,S3) c5_RP(HH26,NN4,HN7,NH7)_HH(P1,A1,S1)_HN(L2,S3)

Interface Class

Interface ID	Interface 1						Interface 2
	Domain	Number of contact residues	Binding site Class	Percentages of Secondary structures(%)			Domain	Number of contact residues	Binding site Class	Percentages of Secondary structures(%)
	Domain	Number of contact residues	Binding site Class	H	E	N	Domain	Number of contact residues	Binding site Class	H	E	N
4u7w_AB	A	14	HN	57.1	100	42.9	B	15	HN	60	0	40

Interface Type: Information for each interface

Interface ID	chain	Number of contact residues			Number of elements					Number of contacts between Secondary structure elements
		Number of contact residues			Number of elements					HH			EE						HE			HN		EN
		Hn	En	Nn	H	E	N	R	L	P	A	S	P	A	S	Ph	Ah	Ih	P	A	S	L	S	L	S
4u7w_AB	A	8	14	6	3	0	3	0	0	0	0	1	0	0	0	0	0	0	0	0	0	1	2	0	0
4u7w_AB	B	9	0	6	3	0	3	0	0	0	0	1	0	0	0	0	0	0	0	0	0	2	2	0	0

Contact Type: Information of contacts between interfaces

Interface ID	Number of residue pairs between SS elements									Number of contacts between Secondary structure elements
	H-H	E-E	N-N	H-E	H-N	N-E	E-H	N-H	E-N	H-H				E-E					H-E				H-N			E-N
	H-H	E-E	N-N	H-E	H-N	N-E	E-H	N-H	E-N	P	A	S	Ih	P	A	S	IPh	IAh	P	A	S	Ih	L	S	Ih	L	S	Ih
4u7w_AB	11	0	5	0	5	0	0	4	0	2	0	2	0	0	0	0	0	0	0	0	0	0	1	4	0	0	0	0

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
x46338	_	Not Classified	Not Classified 463	Not Classified 463	Not Classified 463	Not Classified 463	Not Classified 46338

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
4u7wA00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
4u7wB00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain