PDB ID : 4xjt [A]
Color
ARa IRb
|
|
a AR:All Residues
b IR:Interface Residues
b IR:Interface Residues
Slab plane
Title
HUMAN CD38 COMPLEXED WITH INHIBITOR 2 [4-[(2,6-DIMETHYLBENZYL)AMINO]- 2-METHYLQUINOLINE-8-CARBOXAMIDE]
Structure Summary
| PDB ID | Mutant | OPM | Pub Med | Method/Resolution | HETNAM |
|---|---|---|---|---|---|
| 4xjt | 26267483 | X-RAY DIFFRACTION/2.6 | 41Z:4-[(2,6-DIMETHYLBENZYL)AMINO]-2-METHYLQUINOLINE-8-CARBOXAMIDE NA7:[(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGENDIPHOSPHATE |
| Chain Formula | ||
|---|---|---|
| Amino Acid sequence | SCOPe Family Level | CATH Homology Level |
| [A] | [A] | [A] |
Structual Classification
SCOPe
| SCOPe ID | Chain | Class | Fold | Superfamily | Family | Protein Domain | Species |
|---|---|---|---|---|---|---|---|
| 276386 | A: | Alpha and beta proteins (a/b) | Flavodoxin-like | N-(deoxy)ribosyltransferase-like | ADP ribosyl cyclase-like | ADP ribosyl cyclase | Human (Homo sapiens) [TaxId: 9606] |
CATH
| CATH ID | Node | Class | Architecture | Topology | Homology |
|---|---|---|---|---|---|
| 4xjtA01 | 1.20.82.10 | :Up-down Bundle | :ADP Ribosyl Cyclase; Chain A, domain 1 | :ADP Ribosyl Cyclase; Chain A, domain 1 | |
| 4xjtA02 | 3.40.50.720 | :3-Layer(aba) Sandwich | :Rossmann fold | :NAD(P)-binding Rossmann-like Domain |
