PDB ID : 4yvf [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CA
DB
Title
STRUCTURE OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
4yvf
26037610 X-RAY DIFFRACTION/2.7 NAI:1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
XFA:2-{[5-CHLORO-2-(4-CHLOROPHENOXY)PHENYL](2-{[2-(METHYLAMINO)ETHYL]AMINO}-2-OXOETHYL)AMINO}-N-(1,3-DIHYDRO-2H-ISOINDOL-2-YL)-N-METHYLACETAMIDE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
310110 A:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseHuman (Homo sapiens) [TaxId: 9606]
310109 A:4-189
A:353-432		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseHuman (Homo sapiens) [TaxId: 9606]
310112 B:190-352Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsFormate/glycerate dehydrogenases, NAD-domainS-adenosylhomocystein hydrolaseHuman (Homo sapiens) [TaxId: 9606]
310111 B:4-189
B:353-432		Alpha and beta proteins (a/b)Flavodoxin-likeFormate/glycerate dehydrogenase catalytic domain-likeS-adenosylhomocystein hydrolaseS-adenosylhomocystein hydrolaseHuman (Homo sapiens) [TaxId: 9606]

CATH
CATH ID Node Class Architecture Topology Homology
4yvfA013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
4yvfA023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
4yvfB013.40.50.1480:3-Layer(aba) Sandwich:Rossmann fold:Adenosylhomocysteinase-like
4yvfB023.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain