OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 5es3 [A4]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Style

Secondary Structure

Download

Slab plane

Direction	Proportion
From front	%
From back	%
Move slab

Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	C
C	D
D	B

Title

CO-CRYSTAL STRUCTURE OF LDH LIGANDED WITH OXAMATE

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
5es3			26717415	X-RAY DIFFRACTION/2.29	OXM:OXAMIC ACID

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
280359	A:160-331	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280358	A:4-159	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280355	B:160-331	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280354	B:5-159	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280356	C:1-159	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280357	C:160-331	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280373	D:160-331	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280372	D:5-159	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280365	E:160-331	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280364	E:2-159	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280369	F:160-331	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280368	F:5-159	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280371	G:160-331	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280370	G:4-159	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280367	H:160-331	Alpha and beta proteins (a+b)	LDH C-terminal domain-like	LDH C-terminal domain-like	Lactate & malate dehydrogenases, C-terminal domain	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]
280366	H:5-159	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	automated matches	automated matches	Norway rat (Rattus norvegicus) [TaxId: 10116]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
5es3A01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
5es3A02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
5es3B01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
5es3B02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
5es3C01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
5es3C02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
5es3D01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
5es3D02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
5es3E01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
5es3E02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
5es3F01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
5es3F02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
5es3G01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
5es3G02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
5es3H01	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
5es3H02	3.90.110.10		:Alpha-Beta Complex	:L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2	:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal