PDB ID : 5g0w [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

Direction Proportion
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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BD
CB
DC
Title
INHA IN COMPLEX WITH A DNA ENCODED LIBRARY HIT

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
5g0w
27864515 X-RAY DIFFRACTION/1.79 9NU:(2S,4S)-N-METHYL-4-[[(2S,3R)-3-[(2-METHYLPROPAN-2-YL)OXY]-2-[[4-(PYRAZOL-1-YLMETHYL)PHENYL]CARBONYLAMINO]BUTANOYL]AMINO]-1-(PHENYLCARBONYL)PYRROLIDINE-2-CARBOXAMIDE
MG:MAGNESIUM ION
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
326704 A:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
326651 B:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
326624 C:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]
326691 D:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesEnoyl-ACP reductaseMycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

CATH
CATH ID Node Class Architecture Topology Homology
5g0wA003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
5g0wB003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
5g0wC003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
5g0wD003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain