OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 5icm [A4]

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Title

17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 14 IN COMPLEX WITH A NON- STEROIDAL INHIBITOR

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
5icm			27362750	X-RAY DIFFRACTION/1.68	F45:[6-(3,4-DIHYDROXYPHENYL)PYRIDIN-2-YL](4-FLUORO-3-HYDROXYPHENYL)METHANONE GLC:ALPHA-D-GLUCOPYRANOSE NA:SODIUM ION NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A4]	[A4]	[A4]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
319505	A:271-271	Artifacts	Tags	Tags	Tags	C-terminal Tags	Synthetic
319504	A:5-256	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Tyrosine-dependent oxidoreductases	Retinal dehydrogenase/reductase 3	Human (Homo sapiens) [TaxId: 9606]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
5icmA00	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain