PDB ID : 5k50 [A2]

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ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AI
BJ
Title
THREE-DIMENSIONAL STRUCTURE OF L-THREONINE 3-DEHYDROGENASE FROM TRYPANOSOMA BRUCEI BOUND TO NAD+ AND L-ALLO-THREONINE REFINED TO 2.23 ANGSTROMS

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
5k50
30198897 X-RAY DIFFRACTION/2.26 ACT:ACETATE ION
ALO:ALLO-THREONINE
GOL:GLYCEROL
NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A2] [A2] [A2]

Interfaces
Interface ID Chain Inaterface
Class		 Interface Type Contact Type
5k50_AB A
B		 HN
HN		 i15_CR(H13,N13)_HH(S2)_HN(L1,S5)
i15_CR(H13,N13)_HH(S2)_HN(L1,S5) 		c6_RP(HH23,NN11,HN11,NH12)_HH(P1,A1,S3)_HN(L2,S6)
c6_RP(HH23,NN11,HN11,NH12)_HH(P1,A1,S3)_HN(L2,S6)

Interface Class
Interface ID Interface 1 Interface 2
Domain Number of contact residues Binding site Class Percentages of Secondary structures(%) Domain Number of contact residues Binding site Class Percentages of Secondary structures(%)
H E N H E N
5k50_AB A 30 HN 53.3 100 46.7 B 30 HN 60 0 40

Interface Type: Information for each interface
Interface ID chain Number of contact residues Number of elements Number of contacts between Secondary structure elements
HH EE HE HN EN
Hn En Nn H E N R L P A S P A S Ph Ah Ih P A S L S L S
5k50_AB A 16 30 14 3 0 4 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2 4 0 0
5k50_AB B 18 0 12 4 0 3 0 0 0 0 4 0 0 0 0 0 0 0 0 0 1 4 0 0

Contact Type: Information of contacts between interfaces
Interface ID Number of residue pairs between SS elements Number of contacts between Secondary structure elements
H-H E-E N-N H-E H-N N-E E-H N-H E-N H-H E-E H-E H-N E-N
P A S Ih P A S IPh IAh P A S Ih L S Ih L S Ih
5k50_AB 36 0 9 0 11 0 0 9 0 0 3 3 0 0 0 0 0 0 0 0 0 0 2 5 0 0 0 0

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
341491 A:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesTrypanosome (Trypanosoma brucei) [TaxId: 5691]
341492 C:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesTrypanosome (Trypanosoma brucei) [TaxId: 5691]
341483 E:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesTrypanosome (Trypanosoma brucei) [TaxId: 5691]
341494 G:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesTrypanosome (Trypanosoma brucei) [TaxId: 5691]
341493 I:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesTrypanosome (Trypanosoma brucei) [TaxId: 5691]
341484 J:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsautomated matchesautomated matchesTrypanosome (Trypanosoma brucei) [TaxId: 5691]

CATH
CATH ID Node Class Architecture Topology Homology
5k50A003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
5k50C003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
5k50E003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
5k50G003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
5k50I003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
5k50J003.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain