OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 6g2u [A6]

Color

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

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Secondary Structure

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Chain

Chain name		Ribbon	Spacefill	Cαonly
OLIGAMI	PDB
A	A
B	B
C	C
D	D
E	E
F	F

Title

CRYSTAL STRUCTURE OF THE HUMAN GLUTAMATE DEHYDROGENASE 2 (HGDH2)

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
6g2u			33421122	X-RAY DIFFRACTION/2.93	CL:CHLORIDE ION NA:SODIUM ION PO4:PHOSPHATE ION

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A6]	[A6]	[A6]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
367423	A:213-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	automated matches	Human (Homo sapiens) [TaxId: 9606]
367422	A:8-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	automated matches	Human (Homo sapiens) [TaxId: 9606]
367531	B:11-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	automated matches	Human (Homo sapiens) [TaxId: 9606]
367532	B:213-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	automated matches	Human (Homo sapiens) [TaxId: 9606]
367375	C:11-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	automated matches	Human (Homo sapiens) [TaxId: 9606]
367376	C:213-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	automated matches	Human (Homo sapiens) [TaxId: 9606]
367367	D:213-503	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	automated matches	Human (Homo sapiens) [TaxId: 9606]
367366	D:8-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	automated matches	Human (Homo sapiens) [TaxId: 9606]
367432	E:10-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	automated matches	Human (Homo sapiens) [TaxId: 9606]
367433	E:213-501	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	automated matches	Human (Homo sapiens) [TaxId: 9606]
367392	F:213-503	Alpha and beta proteins (a/b)	NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	Aminoacid dehydrogenase-like, C-terminal domain	automated matches	Human (Homo sapiens) [TaxId: 9606]
367391	F:8-212	Alpha and beta proteins (a/b)	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenase-like, N-terminal domain	Aminoacid dehydrogenases	automated matches	Human (Homo sapiens) [TaxId: 9606]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology
6g2uA01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
6g2uA02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
6g2uA03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
6g2uB01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
6g2uB02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
6g2uB03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
6g2uC01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
6g2uC02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
6g2uC03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
6g2uD01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
6g2uD02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
6g2uD03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
6g2uE01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
6g2uE02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
6g2uE03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain
6g2uF01	1.10.287.140		:Orthogonal Bundle	:Helix Hairpins	:
6g2uF02	3.40.50.10860		:3-Layer(aba) Sandwich	:Rossmann fold	:Leucine Dehydrogenase, chain A, domain 1
6g2uF03	3.40.50.720		:3-Layer(aba) Sandwich	:Rossmann fold	:NAD(P)-binding Rossmann-like Domain