PDB ID : 6gpj [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BD
CC
DB
Title
CRYSTAL STRUCTURE OF HUMAN GDP-D-MANNOSE 4,6-DEHYDRATASE IN COMPLEX WITH GDP-4F-MAN

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
6gpj
30984471 X-RAY DIFFRACTION/1.94 CIT:CITRIC ACID
EDO:1,2-ETHANEDIOL
G4F:[[(2~{R},3~{S},4~{R},5~{R})-5-(2-AZANYL-6-OXIDANYLIDENE-1~{H}-PURIN-9-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHOXY-OXIDANYL-PHOSPHORYL] [(2~{R},3~{S},4~{R},5~{S},6~{R})-5-FLUORANYL-6-(HYDROXYMETHYL)-3,4-BIS(OXIDANYL)OXAN-2-YL] HYDROGENPHOSPHATE
NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
354951 A:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesGDP-mannose 4,6-dehydrataseHuman (Homo sapiens) [TaxId: 9606]
354974 B:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesGDP-mannose 4,6-dehydrataseHuman (Homo sapiens) [TaxId: 9606]
354946 C:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesGDP-mannose 4,6-dehydrataseHuman (Homo sapiens) [TaxId: 9606]
354977 D:22-22ArtifactsTagsTagsTagsN-terminal TagsSynthetic
354976 D:23-372Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesGDP-mannose 4,6-dehydrataseHuman (Homo sapiens) [TaxId: 9606]

CATH
CATH ID Node Class Architecture Topology Homology
6gpjA013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
6gpjA023.90.25.10:Alpha-Beta Complex:UDP-galactose 4-epimerase; domain 1:UDP-galactose 4-epimerase, domain 1
6gpjB013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
6gpjB023.90.25.10:Alpha-Beta Complex:UDP-galactose 4-epimerase; domain 1:UDP-galactose 4-epimerase, domain 1
6gpjC013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
6gpjC023.90.25.10:Alpha-Beta Complex:UDP-galactose 4-epimerase; domain 1:UDP-galactose 4-epimerase, domain 1
6gpjD013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
6gpjD023.90.25.10:Alpha-Beta Complex:UDP-galactose 4-epimerase; domain 1:UDP-galactose 4-epimerase, domain 1