PDB ID : 6gpk [A4]

Color

ARa IRb





 a AR:All Residues
 b IR:Interface Residues

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Secondary Structure


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Slab plane

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Chain
Chain name Ribbon Spacefill Cαonly
OLIGAMI PDB
AA
BB
CC
DD
Title
CRYSTAL STRUCTURE OF HUMAN GDP-D-MANNOSE 4,6-DEHYDRATASE (E157Q) IN COMPLEX WITH GDP-MAN

Structure Summary
PDB ID Mutant OPM Pub Med Method/Resolution HETNAM
6gpk
30984471 X-RAY DIFFRACTION/1.47 EDO:1,2-ETHANEDIOL
GDD:GUANOSINE-5___sq___-DIPHOSPHATE-ALPHA-D-MANNOSE
GOL:GLYCEROL
NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Chain Formula
Amino Acid sequence SCOPe Family Level CATH Homology Level
[A4] [A4] [A4]

Structual Classification
SCOPe
SCOPe ID Chain Class Fold Superfamily Family Protein Domain Species
354959 A:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesGDP-mannose 4,6-dehydrataseHuman (Homo sapiens) [TaxId: 9606]
354953 B:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesGDP-mannose 4,6-dehydrataseHuman (Homo sapiens) [TaxId: 9606]
354978 C:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesGDP-mannose 4,6-dehydrataseHuman (Homo sapiens) [TaxId: 9606]
354952 D:Alpha and beta proteins (a/b)NAD(P)-binding Rossmann-fold domainsNAD(P)-binding Rossmann-fold domainsTyrosine-dependent oxidoreductasesGDP-mannose 4,6-dehydrataseHuman (Homo sapiens) [TaxId: 9606]

CATH
CATH ID Node Class Architecture Topology Homology
6gpkA013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
6gpkA023.90.25.10:Alpha-Beta Complex:UDP-galactose 4-epimerase; domain 1:UDP-galactose 4-epimerase, domain 1
6gpkB013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
6gpkB023.90.25.10:Alpha-Beta Complex:UDP-galactose 4-epimerase; domain 1:UDP-galactose 4-epimerase, domain 1
6gpkC013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
6gpkC023.90.25.10:Alpha-Beta Complex:UDP-galactose 4-epimerase; domain 1:UDP-galactose 4-epimerase, domain 1
6gpkD013.40.50.720:3-Layer(aba) Sandwich:Rossmann fold:NAD(P)-binding Rossmann-like Domain
6gpkD023.90.25.10:Alpha-Beta Complex:UDP-galactose 4-epimerase; domain 1:UDP-galactose 4-epimerase, domain 1