OLIGAMI : Oligomer Architecture and Molecular Interface

PDB ID : 6u49 [A7]

AR^a IR^b

Chain(OLIGAMI)
Chain(PDB)
Domain
CPK
Secondary Structure
Polar(blue)/
Nonpolar(white)

^a AR:All Residues
^b IR:Interface Residues

Title

STRUCTURE-BASED DISCOVERY OF A NOVEL SMALL-MOLECULE INHIBITOR OF METHICILLIN-RESISTANT S. AUREUS

Structure Summary

PDB ID	Mutant	OPM	Pub Med	Method/Resolution	HETNAM
6u49			32179646	X-RAY DIFFRACTION/2.35	PQJ:FOS-CHOLINE-14 SO4:SULFATE ION

Chain Formula
Amino Acid sequence	SCOPe Family Level	CATH Homology Level
[A7]	[A7]	[A7]

Structual Classification

SCOPe

SCOPe ID	Chain	Class	Fold	Superfamily	Family	Protein Domain	Species
382803	A:	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	Leukocidin (pore-forming toxin)	Alpha-hemolysin	Staphylococcus aureus [TaxId: 1280]
382893	B:	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	Leukocidin (pore-forming toxin)	Alpha-hemolysin	Staphylococcus aureus [TaxId: 1280]
382823	C:	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	Leukocidin (pore-forming toxin)	Alpha-hemolysin	Staphylococcus aureus [TaxId: 1280]
382910	D:	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	Leukocidin (pore-forming toxin)	Alpha-hemolysin	Staphylococcus aureus [TaxId: 1280]
382851	E:	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	Leukocidin (pore-forming toxin)	Alpha-hemolysin	Staphylococcus aureus [TaxId: 1280]
382806	F:	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	Leukocidin (pore-forming toxin)	Alpha-hemolysin	Staphylococcus aureus [TaxId: 1280]
382852	G:	Membrane and cell surface proteins and peptides	Leukocidin-like	Leukocidin-like	Leukocidin (pore-forming toxin)	Alpha-hemolysin	Staphylococcus aureus [TaxId: 1280]

CATH

CATH ID	Node	Class	Architecture	Topology	Homology